Human neutrophil heterogeneity exists, but is it meaningful?

Human neutrophil heterogeneity exists, but is it meaningful?

By John I. Gallin N EUTROPHILS are one of the major phagocytes of the body’s defenses, and they have long been considered a homogeneous cell population that seeks and destroys pathogens and then mysteriously disappears into oblivion. In recent years, it has become clear that the concept of neutrophil homogeneity is not valid, and peripheral blood neutrophils have been shown to be heterogeneous ...

Thymoma calcification: Is it clinically meaningful?

Among anterior mediastinal lesions, thymoma is the most common. Thymomas are tumors of thymic epithelial cell origin that are distinguished by inconsistent histological and biologic behavior. Chest imaging studies typically show a round or lobulated tumor in the anterior mediastinum. Calcifications in thymomas are classically punctuate or amorphous, positioned within the lesion. Chest computed ...

Heterogeneity in Human Neutrophil , M acrophage

Progenitor cells of neutrophils, monocytemacrophages, and eosinophils in human marrow were enumerated in agar cultures stimulated by placental conditioned medium or white cell underlayers. Fractionation of marrow populations by velocity sedimentation showed that the profiles of neutrophil and macrophage colony-forming cells shifted from a peak of 8-9 mm/hr in 7-day cultures to a peak of 6-7 mm/...

What is heterogeneity and is it important?

But Is It Phenomenology?